Do you want to apply your physics and technical talents to improve the perspectives of pancreatic cancer patients? Do you have MRI and programming skills and eager to work in a stimulating multidisciplinary environment? Then we certainly would like to get to know you. Your job will be to clinically implement technologies newly developed by our group that allow for safe tumor dose escalation while simultaneously sparing all bowel structures in the treatment of pancreatic cancer patients. The new treatment workflow will enable online target and organs at risk visualization, online treatment plan adaptation, and real-time target tracking. You will participate in three work packages that have been defined in this project:
WP1: tumor motion assessment using dedicated MRI sequences.
Here you will assess the 3D motion characteristics of both the tumor of surrounding radiosensitive bowel structures at high temporal resolution over the entire treatment course in a series of 30 pancreatic cancer patients using dedicated MRI sequences that are acquired during dose delivery.
WP2: Development of novel dose guided treatment strategies for MRLinac based pancreatic cancer treatments
Here you will develop an adaptive treatment workflow where the actual delivered dose is used to steer the planning objectives for the remaining fractions. Aim is to fully utilize the therapeutic bandwidth between bowel toxicities and optimal tumor control allowing safe delivery of high ablative dose levels to the tumor.
WP3: Development, validation and clinical implementation of dose guided treatment regimen
Here the tools and strategies you have developed in WP2 will be tested, validated and clinically implemented in a new cohort of 30 patients. The research tools need to be migrated to the quality management system for clinical software development in our department.
All work will be carried out in close collaboration with clinical physicists, MR physicists, radiation oncologists, clinical researchers and radiation technology therapists.
The radiotherapy department of the UMC Utrecht has been pioneering MR-guided radiotherapy for over decades and is internationally widely recognized as one of the key players in this field. Together with Elekta and Philips we have developed a linear accelerator with integrated 1.5T MRI functionality, which is now commercially available as the Elekta Unity MR-linac system. The improved online image guidance of MR-linac will ultimately allow for more precise stereotactic radiotherapy of tumors in the thoracic, abdominal and pelvic region. Recently, our department was awarded a KWF grant to develop an online adaptive treatment strategy for pancreatic cancer.
You have an MSc degree in (applied) physics, biomedical engineering, medical imaging, computer science or a related field, with experience in scientific reporting image processing, and computer programming. MRI skills will be appreciated. You are enthusiastic about closely working together with other members of our multidisciplinary radiotherapy team and motivated to write scientific papers on the results of the project and give presentations at national and international meetings.
The salary for this 100% function is still to be determined. This job is based on a temporary position for 4 years.
In addition, we offer an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities. The terms of employment are in accordance with the Cao University Medical Centers (UMC).
If you have any questions about this vacancy, please contact Mr.Gert Meijer, Clinical Physicist, phone number: +31 (0)88 75 539 20, e‑mail adress: email@example.com.
Acquisition based on this jobopening is not appreciated.