Your main goal will be to better understand the regulation of bone pain induced by cancer. You will specifically investigate mitochondrial regulation of bone pain. You will focus on exploring the changes and functional role of mitochondrial specific functions in sensory neurons and osteoclasts that are linked to bone pain. You will be using animal models, perform behavioral tests, and combine molecular and biochemical assays including intravital imaging.
As PhD fellow you will participate in the EU-funded Innovative Training Network BonePainII (www.bonepain.eu). BonePainII is a European Innovative Training Network to promote frontline research, innovation and education within bone pain. Millions in Europe and beyond suffer from bone pain, which is a debilitating complication of many musculoskeletal disorders such as arthritis and bone metastasis. Your key tasks as a PhD fellow are to manage and carry through your research project, participate in the BonePainII training and network activities, take PhD courses, write scientific articles and your PhD thesis, participate in national and international congresses and scientific meetings, research stay at an external research laboratory within the BonePainII network and disseminate your research. Expected start as soon as possible, but before 15 december 2019.
You will work in the neuro-immunology pain group of Niels Eijkelkamp, which is part of the Laboratory of Translational Immunology at the University Medical Center (UMC) Utrecht, the Netherlands. You will be part of a team of PhD students, post-docs and research technicians that are actively collaborating on projects to better understand chronic pain and develop novel therapeutic strategies to kill pain. More info: https://www.umcutrecht.nl/en/Research/Research-programs/Infection-Immunity/Research-Groups/Group-Eijkelkamp.
The BonePainII network has participants from six European countries and encompasses eight academic groups and four industries all committed to creating an outstanding training program for fifteen early stage researchers (ESRs) to elucidate the mechanisms of bone pain and develop new medicines. The project is funded by the European Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 814244.
We are looking for a highly-motivated, excellent candidate with a MSc degree in biomedical sciences with an interest in neuroscience, pre-clinical studies with in vivo animal research including behavioral paradigms and molecular techniques. You have an affinity for molecular and biochemical techniques. You are challenged by novel scientific concepts, flexible, and like to work in an interdisciplinary team. Preferentially you have experience in animal research and/or a master in neuroscience. Experience with bone cancer pain research will be an advantage. Fluency in English is a requirement. There are strict mobility and eligibility criteria. You must not have resided or carried out your main activity (work, studies, etc.) in the Netherlands for more than twelve months in the last three years immediately prior to your recruitment – unless as part of a procedure for obtaining refugee status under the Geneva Convention. You must be an Early-Stage Researcher (ESR): at the date of recruitment you must be in the first four years (full-time equivalent research experience) of your research career and must not have not been awarded a doctoral degree. Key criteria for the assessment of the applicant: relevant skills and knowledge; previous publications; relevant work experience; the grades achieved during bachelor/master studies; other professional activities; language skills; assessment of the candidate’s motivation letter.
The maximum salary for this position (100%) is € 3.103,00 gross per month based on full-time employment (work week 36 hours). This job is based on a temporary position for 3-4 years.
In addition, we offer an annual benefit of 8.3%, holiday allowance, travel expenses and career opportunities. The terms of employment are in accordance with the Cao University Medical Centers (UMC).
If you have any questions about this vacancy, please contact Mr.Niels Eijkelkamp, Associate Professor, phone number: 088 75 543 54, e‑mail adress: firstname.lastname@example.org.
Acquisition based on this jobopening is not appreciated.